Apply once a day in the evening.

Arbutin 7%. Inactive Ingredient: Water, Glycerin, Cetyl Alcohol, PPG-2 Myristyl Ether Propionate, Sodium Lauryl Sulfate, TEA-Salicylate, Tocopheryl Acetate (Vitamin E), Ascorbic Acid, Lactic Acid, Phenyl Trimethicone, Sodium Metabisulfite, BHT, Saponins, Disodium EDTA, Methylparaben, Propylparaben.

1) As a precaution, Arbutin based products (Obagi Nu-Derm Clear Fx and Obagi Nu-Derm Blend Fx) should not be used by pregnant women, women who intend to become pregnant in the near future, or women who are lactating/breast feeding

2) Obagi Nu-Derm Clear Fx and Obagi Nu-Derm Blend Fx contain sodium metabisulfite, a sulfite that may cause allergic-type reactions (e.g. hives, itching, wheezing, anaphylaxis, severe asthma attacks) in certain susceptible people. Test for skin sensitivity before using by applying a small amount to an unbroken patch of skin and check within 24 hours. If itching or vesicle formation or excessive inflammatory response occurred, product should be discontinued and clinician consulted.